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Injections for Tendon Pain

1/12/2020

 
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​I’ve been frustrated this week by a couple of patients with Achilles problems that I thought should recover well. They’ve disappeared to go and have an injection, against my recommendation. It’s made me think about whether or not I should have made the referral myself? What are our options for injections, and do they work?

​TENDON PAIN

Tendinopathy (tendon pain) is very common.  They are the most common type of overuse injury (ref). Achilles tendinopathy affects the majority of runners (ref) and is the reason 16% of athletes have to stop sports participation (ref).

There are a range of commonly prescribed treatment options for tendinopathy, but very few are supported by quality, randomised, prospective, placebo-controlled trials.

​SO WHAT DO I DO?

Considering all the available treatment options, above anything else, I always recommend:
  • load management, in combination with
  • a strengthening program.  

​WHAT ABOUT INJECTIONS?

​Having mapped out a management plan, patients will routinely ask my opinion on getting an injection. They may have had a friend for whom an injection worked well, or the GP has suggested it as an option, or they’ve had one before and it worked.  

There are a range of drugs to inject into or around a tendon, depending on who you are referred to:
  • Corticosteroid (A strong anti-inflammatory)
  • Prolotherapy (An irritant to stimulate new tissue growth, e.g. hypertonic dextrose/glucose)
  • Sclerotherapy (An irritant to decrease vascularisation, e.g. Polidocanol)
  • Traumeel (A homeopathic preparation derived from arnica)
  • Actovegin (derived from calf blood)
  • Autologous blood (injecting your own blood into the tendon to promote healing)
  • Platelet-rich plasma (blood is taken and PRP is extracted and injected to promote healing)
  • High-volume injections (to damage the tissue and encourage new growth)

​CORTICOSTEROIDS

Corticosteroids are an anti-inflammatory medication injected around the tendon to decrease pain that is caused by inflammation (although it is now thought that inflammation does not play a significant role in tendon pain). Corticosteroid injections have historically been commonly prescribed but more recently their use is controversial. Repeated corticosteroid injections can weaken the tendon and increase the risk of rupture. Corticosteroid injections are good at relieving pain in the short term (2-6 weeks) however, there is strong evidence that long-term outcomes (> 6 months) are worse than other conservative treatments or no treatment at all (ref).

"The best systematic review evidence shows that local corticosteroid injections are not effective for tendinopathies after the first few weeks, and produce worse long-term outcomes compared to other treatments" (ref)
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​PROLOTHERAPY / SCLEROTHERAPY

Prolotherapy injections act as an irritant causing an inflammatory response then scarring of the nerves that transmit pain. There is no solid support in the medical literature for this procedure for the treatment of tendinopathies. A randomised controlled trial of polidocanol injections showed the potential to reduce tendon pain in patients with chronic painful mid-portion Achilles tendinopathy (ref). However, a systematic review found limited results for use of prolotherapy in sports related soft tissue injuries (ref).  

​AUTOLOGOUS BLOOD INJECTIONS

The rationale of autologous blood injection consists of enhancing tendon healing through collagen regeneration and the provision of cellular mediators. Good experimental models are lacking, and clinical application is anecdotal. A 2013 randomised controlled trial investigating the efficacy of autologous blood injections as a treatment for mid-portion Achilles tendinopathy concluded they did not reduce pain or improve function any more than a strengthening program. (ref)  

​HIGH-VOLUME INJECTIONS

The suggested mechanism of high-volume injections is the mechanical disruption of local tissues then stimulates a healing response.  One study (ref) has shown that high-volume injection of normal saline solution, corticosteroids or anaesthetics reduces pain and improves short and long-term function in patients with Achilles tendinopathy. However, more research is required.

​PLATELET RICH PLASMA (PRP)

Platelets are naturally occurring in your blood, where they play an important role in healing damaged tissue, so superficially it’s inherently appealing to just add more of them to the sore spot. PRP injections are particularly trendy at the moment and it’s easy to find someone who will tell you they work well.  Unfortunately, research concludes there is no benefit to PRP injections. This study found PRP injections do not improve plantar fasciopathy pain or function. This study concluded there is insufficient evidence to support the use of PRP for treating musculoskeletal soft tissue injuries. This systematic review found strong evidence against platelet-rich plasma injections for tennis elbow. This study found PRP did not improve tendon structure. This meta-analysis found no greater clinical benefit of PRP over placebo or dry needling for tendinopathy.

​SO…

​Would I have any of these injections, or would I recommend them to my patients, friends, or family? Well it depends. In my experience some people get some benefit some of the time. HOWEVER, these injectables are not consistently effective and their use is mostly not supported by research. I suggest that patients try the strengthening program and the results will be overall better in the long term.  

​WHY DO THE INJECTIONS WORK FOR SOME PEOPLE?

​I’ve been frustrated with a couple of patients that cancelled their follow-up appointment and, when I phoned and asked what had happened, they’ve had an injection and now feel fine. My conclusion is the injections don’t work, but if you were sore and now you’re not, your conclusion would be they do work. So what is it?..

​REGRESSION TO THE MEAN

​Most people seek treatment when they are at their worst. By definition the only possible change from being as bad as at can be, is an improvement. Was it the injection working, or was it getting better anyway?

​NATURAL HISTORY

​Some conditions are self limiting and will just get better by themselves. Did the injection work, or was it about to get better anyway?

​PLACEBO

Injections are a powerful way to administer a placebo effect. You need to see a specialist to receive it. You need to pay more money. There’s some high-tech equipment spinning the blood. Everything is set up for you to expect improvement and, in a decent percentage of cases, that’s all it takes to get better. If you believe the injection will help you then it is much more likely to work. However, the research tells us it doesn’t really matter what substance is injected, it is your belief in whether or not it will help that is the variable more likely to determine the outcome.
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​SUMMARY

I understand that getting an injection seems like a much easier option than doing 12-weeks of strengthening exercises, but in the long run, a strengthening program is the thing that actually works.

​TL;DR

If treating tendon pain was as easy as getting an injection then that’s what everyone would do first. Unfortunately it’s not as easy as that.

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Are You Out Of Alignment?

20/11/2020

 
​I treat a lot of people that have:
  • back pain,
  • neck pain,
  • pelvis pain,
  • hip pain.


​Very commonly they’ll tell me something is “out of alignment”. Either that’s what it feels like, or they’ve had treatment from a therapist that has told them that, or they’ve talked to a friend who has said “maybe your ‘X’ is out?” and that makes perfect sense to them.

The concept of something being “out of alignment” is not a paradigm I’ve ever been taught or taught to patients. My understanding of it as an idea is that it comes from an osteopathic and chiropractic model where pain and illness are meant to originate from vertebral “subluxations”. A vertebra is “out of place”. The subluxation model is now being discouraged by chiropractic associations worldwide as not being valid, but it has definitely seeped into public consciousness. A lot of people when they have back pain will try and describe how it feels and come up with the explanation that they’ve “put their back out”. Patients grab hold of a simple idea that seems to makes sense.

When a patient uses this sort of terminology I used to play along with it because I understood what they were saying and I found I upset a lot of patients if I tried to correct them. They had paid good money to see a chiropractor who’s told them their pelvis was out of alignment, they’ve agreed that’s what it felt like so they’ve bought into the idea. When I question the concept directly it can be upsetting. If someone to whom you’ve paid money tells you something, and they’re a nice enough person, and they seem like they care about you and know what they’re talking about, you believe them. To then be the second therapist offering an opinion and say something different can be tricky and I usually word it incorrectly and put the patient right off side.
Anyway, I used to let it slide because it’s easier for everyone, I can get on with treatment using my own paradigm, and I didn’t think any harm was done.

But I’ve now changed my mind on staying quiet. 

I saw a lady today who’s been seeing an osteopath twice a week for a year - thousands of dollars - for a radiculopathy from her lumbar spine which has now progressed to a foot drop. Every session her “pelvis was out”. She doesn’t know how it keeps happening. Her only solution was to pay this “expert” for a “re-alignment”. It’s a very common story. I got so upset today. This lady was in tears - she felt so helpless.

I think this sort of treatment is criminal. It makes someone a helpless victim by diagnosing them with something that they have absolutely no control of themselves - the pelvis just keeps going out mysteriously. And sell a solution: “I can put it back for you. Come in twice a week”. Nothing you can do to help yourself. 

The language is dangerous and damaging and takes advantage of a patient that trusts you are a professional providing an honest service.

When a therapist talks about something being out of alignment I hope they are using the terminology as a euphemism rather than believing something is actually out of place. Because we know it’s not. 

So the therapist is either:
  • unknowingly perpetuating an idea that is harmful because they are ignorant,
  • or deliberately deceiving patients for financial gain.

So I’m no longer tolerating the language of something being out of place or out of alignment.

​It’s not, and it’s harmful to talk like that.


​I used to think physios were better than that and the language of alignment was just for other professions. I used to be OK with it because it was Chiro’s and Osteo’s, not physios. But more often these days the language of something being “out” is creeping into physiotherapy. Muscle Energy Technique (MET) is a type of treatment physios are using to treat the hips, sacrum, pelvis, and back pain. “Rotations”, “counter-rotations”, “up-slips”, and “down-slips”. The way they teach it seems like they actually believe it’s a physical/mechanical movement rather than a conceptualised euphemistic explanation. I don’t think it’s a path the physio profession should go down. 

I understand how it happens. An “expert” is in town selling a course. You pay money for the course, you’ve bought the product and are invested in it working, you give it a go with patients and get good results. It’s the same cascade that makes the patient buy in.

Next minute it seems like everyone’s pelvis is twisted. It’s an epidemic.
How can different professions, and even two therapists in the one profession, come up with completely different explanations for what’s going on? I think that speaks to the size of the problem of back pain and there not being a single treatment option that helps everyone. (Well actually there is and that’s exercise - but it’s harder for people to make money from selling exercise.)

This is a bit of a rant and I’m almost nervous to write it down because there are some well respected therapists across a number of professions who are a lot smarter, have better jobs, and earn a lot more money than me, who speak about things being out of alignment.

Not me. Don’t worry. Your back is strong. Your back is stable. Your back is resilient. It’s sore now, but that is largely unrelated to structure and mechanics. There’s definitely nothing broken, out of place, or alignment.


ITB (RUNNER'S KNEE)

11/11/2020

 
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ITB = Ilio-Tibial Band. The ITB is a muscle that runs from the ilium to the tibia. The ilium is the boney wing of your pelvis. The tibia is the big leg bone between your knee and ankle. The ITB has a short little contractile muscle belly on the side of your hip, and a long, non-contractile tendon down the side of your thigh, that anchors onto the bone on the outside of the knee. And that’s where it gets sore in runners. ITB soreness is called “runner’s knee”.

Tendons are the weak link when we overtrain or start new exercise programs. The muscle belly has a good blood supply. We draw them as red on anatomy posters, and the tendon we draw as white, representing the fact that it doesn’t have as much blood. When we train, the muscle belly copes well with whatever we throw at it, but the tendon can let us down. All the overtraining injuries we get are sore tendons: Achilles, ITB, Tennis Elbow, sore Rotator Cuffs, etc. Tendons don’t like the combination of load and stretch. Achilles get sore when we run up hill, putting the tendon on a stretch. Tennis elbows get sore when we hit backhands “late”, which combines stretch and load to the tendon.

ITBs don’t like the stretch/load combination in runners who let their knees turn in.

Ultimately, doing too much too quickly is the cause. Because it would never be sore if you never ran. But the biomechanics of your gait are a contributor. It’s more common in women than men, because women have wider pelvises, their thigh bones start wider apart at the top, and angle in more than men’s (called a Q-angle). We test a single leg squat and see where your knee points, in relation to your foot, and that predicts where your knee travels when you run. Ideally we like the knee to move over the foot. In runners who get runner’s knee, we often see your knee travels more to the inside of the foot. We call this femero-tibial internal rotation. People commonly call it "knock knees”. Biomechanical contributors to this can be:
  • Over-pronation in the foot
  • Fatigue in glutes. Your bum muscles help hold you up straight. Under-utilise your glutes and the hips move more laterally, which increases stretch on the ITB.

Letting the knee twist in, or the hips move out laterally, puts the ITB on more of a stretch. The ITB protests by getting sore.

There’s usually a spike in training load that sets it off. One long run, or more runs per week than usual. If you increase gradually, it adapts.

The initial pain is inflammatory, although it doesn’t always look swollen. If you can rest it for a couple of weeks, and treat it with ice and anti-inflammatory tablets, it usually settles down well. If you run on it when it’s already sore, it can turn into a more chronic problem that takes ages to heal.

I get people to not run for 2 weeks, while you do a couple of strength/control exercises:
  1. Single leg squat in the mirror, slow and controlled, not too deep, aiming to control the knee travelling over the little toe. 10 Reps, 3/day.
  2. Crab walk. Theraband around the feet. 1/2 squat and stay low. Step apart and together, side to side, staying low. 20 reps, 3/day. It gets you feeling what using your glutes feels like.

On the second week I get you to increase your walking distance.

Once you can go for a decent walk without the knee being sore, I’ve got a jogging program that builds you up from 1min through to a 5km, over three or 4 weeks. We add in harder strength exercises as you go.​

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